Before I went to San Diego everyone told me that I would HAVE to visit the Hotel del Coronado. I marked it down, but had no plans of visiting it, until I ran out of things to do on the last day there.
What a waste of time.
If it was something you have to do, go ahead and do it. But the majestic bridge leading out to the island can be viewed nicely from Downtown, and the Hotel as a tourist site is only okay.